Receptor
|
Sympathetic
|
Major function
|
α1
|
↑ vascular smooth muscle contraction, ↑pupillary dilator muscle contraction (mydrasis), ↑ intestinal and bladder sphincter muscle contraction
| |
α2
|
↓ sympathetic outflow, ↓ insulin release
| |
β1
|
↑ heart rate, ↑ contractility, ↑ renin release, ↑ lipolysis
| |
β2
|
Vasodilatation, bronchodilation, ↑ heart rate,
↑ contractility
↑ lipolysis, ↑ insulin release, ↓ uterine tone
| |
M1
|
Parasympathetic
|
CNS, enteric nervous system
|
M2
|
↓ heart rate and contractility of atria
| |
M3
|
↑ exocrine gland secretions, ↑ gut peristalsis, ↑ bladder contraction, bronchoconstriction, ↑ pupillary sphincter muscle contraction (miosis), ciliary muscle contraction (accommodation)
| |
D1
|
Dopamine
|
Relaxes renal vascular smooth muscle
|
D2
|
Modulates transmitter release, especially in brain
| |
H1
|
Histamine
|
↑ nasal and bronchial mucus production, contraction of bronchioles, pruritus, and pain
|
H2
|
↑ gastric acid secretion
| |
V1
|
Vasopressin
|
↑ vascular smooth muscle contraction
|
V2
|
↑ H₂O permeability and reabsorption in the collecting tubule of the kidney (V2 is found in the 2 kidneys)
|
fuente: Le, Bhushan & Grimm 2011, First AID for the USMLE step 1
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