Tuesday, November 19, 2013

MULTIPLE MYELOMA

Clinical
  • Average age is 60-70
  • Men much more common than women
  • Most have an elevated serum protein with 80-90% in the globulin fraction, especially IgG
  • Bence-Jones protein in 40-60% of patients (light chains)
  • X-ray findings
    • Osteoporosis is most common skeletal abnormality in this disease
    • Lesions are usually multiple and found in vertebrae, ribs, skull, pelvis, and femur
    • Over 50% of solitary lesions are found in vertebrae
    • Mandible involved in 1/3 of patients with diffuse involvement
    • Widespread lucencies in bone
      • Discrete, “punched-out” lesions
      • Uniform in size
    • Distinctive to MM are the lucent, elliptical, subcortical shadows, especially in long bones=endosteal scalloping
      • Due to buttressing since MM is usually a slower process than mets
    • In spine, MM destroys body and spares pedicle
  • DDX: mets and disuse osteoporosis
    • MM is more widespread
    • More discrete holes in MM
    • Large foci of coalescence more often due to mets
    • Severe disuse osteoporosis may simulate bone changes of MM
  • Sclerosis is usually seen only with treatment or fracture
    • Bone scans may typically be negative and many hot  areas on scan may be healing fractures
  • Most believe that almost all patients with a solitary plasmacytoma will develop multiple myeloma
    • Solitary plasmacytoma produces “soap-bubbly” expansile, septated lesion, when characteristic
  •  

    Thursday, November 14, 2013

    ERGONOMIC IN THE WORKPLACE


    Each year, employees miss work and potential wages due to work-related musculoskeletal disorders (MSDs). According to the Bureau of Labor Statistic (BLS), 335,390 American workers experienced MSDs serious enough to require time off work in 2007.

    In fact, injuries to the muscles and skeleton are among the most common lost time illnesses and injuries in virtually every industry.

    Musculoskeletal disorders occur when there is a mismatch between what your job requires you to do and what your body is capable of doing. MSDs can affect worker in job activities across many diverse workplaces and tasks.

    The Institute of Medicine estimates that the economic burden of MSDs in the workplace, as measured by compensation costs, lost wages, and lost productivity, are between $45 and $54 billion annually. Historically, overexertion, one form of MSDs, is the number one cause of workplace injury.

    In 2007, there were 1,2 million MSD cases requiring days away from work in private industry out of 4 million total recordable cases. Of these, 335, 390 cases required an average of nine days away from work, two more days than the average for all days away from work cases.

    Because of statistics like these, ergonomics has become an important and serious issue for industry.

    The term “ergonomic” is derived from two Greek words: “erg” meaning work and “nomas” meaning natural laws.

    Basically, ergonomics is the science of adjusting job conditions, equipment, and tasks to match the body’s natural ways of functioning.

    The goal of ergonomics is to prevent illness and injury, assure high productivity, and promote satisfaction in the workplace.

    In the absence of a federal ergonomics standard, the Occupational Safety and Health Administration (OSHA) has addressed ergonomics in the workplace under the authority of section 5 (a)(1) of the Occupational Safety and Health Act.

    This section is referred to as the General Duty Clause and requires employers to provide work and a work environment free from recognized hazards.

    Many employers have realized that the implementation of an ergonomics program is in their best interest for the reduction of injuries and illnesses.

    An ergonomics program addresses some basic elements such as employers and employee responsibilities, hazards identification and information, job hazard analysis and control, training, medical management, records, and programs evaluation.

    Your company’s ergonomics programs is designed to help keep you healthy, productive and motivated while making your working life as enjoyable as possible.

    Your company can express its commitment in a variety of ways. These include holding employee meeting to discuss ergonomics operational goals and priorities that are firm, achievable, and in line with cost reduction, productivity, and quality initiatives.

    In addition, your employer may commit resources to training, administrative needs, expertise, and ergonomics improvements or issue policy statements that define support and cooperation from management, supervision, and employees.

     

    Musculoskeletal Disorders (MSDs) definitions: Are disorders of the muscles, ligaments, tendons, cartilage, joints, nerves, or spinal discs that have been diagnosed by physical exam, medical history, or specific medical test.

    They typically result from gradual or chronic development, as opposed to an acute event or injury caused by, for example, a slip or fall. MSDs like carpal tunnel syndrome have very distinct signs and symptoms. Other disorders, such as lower back pain, are simply defined by the location of the pain.

    To better understand ergonomics, you should be familiar with the major parts of the musculoskeletal system:

    Ø Bones: Provide structural support and are connected to one another at joints, which allow movement between body segments.

    Ø Muscles: Contract and shorten, causing movement, just contract to provide stability. The respiratory and circulatory systems supply nutrients and oxygen necessary for movement of muscles.

    Ø Ligaments and tendons: ligaments connect bone to bone and provide stability at the joints, while tendons attach muscle to the bone.

    Ø Cartilage: Provides the joints with low friction surface that help with movement.

    Ergonomics Awareness

    Recognizing the early signs and symptoms of injuries to the muscles and skeleton and reporting them as soon as possible is very important. A health care provider (HCP) can observe the signs. Symptoms, however, are subjective and a patient needs to report them to HCP.

    Signs of injury to the muscles and skeleton include redness or loss of color, swelling, loss of function, deformity such as a lump, decreased range of motion, and decreased grip strength.

    Symptoms are your body’s way of warning you that you may be developing an injury. Symptoms of injury to the muscles and skeleton can vary in severity, depending on the amount of your exposure.

    Eventually the symptoms become more severe as exposure continues and will appear even after rest. The pain may increase to a point where it becomes difficult to perform your work or even to a point where you are unable to perform any physical work activities.

    Examples of symptoms of injury to the muscles and skeleton include numbness, burning, tingling, aching, pain or soreness, stiffness, and cramping.

    Early reporting is vital in preventing or minimizing injury to the muscles and skeleton. As an employee, you must feel free to report any signs or symptoms of physical discomfort as soon as possible to your supervisor or other personnel, such as a plant nurse or HCP.

    Employers can also gather information by conducting symptoms surveys and interviews.

    Risk Factors

    The OSHA has identified a high rate of injury among workers in various industries. It is impossible to determine the exact weight lifted or the number of repetition that will either cause or prevent injury.

    However, establishing a systematic approach to address such issues as repetition, excessive force, awkward posture, and heavy lifting reduces the chance that you may ne injured.

    Identifying risk factors in the workplace, before injuries to the muscle and skeleton are discovered, is an important step in keeping you healthy.

    Your employer can use several methods to detect risk factors, such as interviews with workers and supervisors, and walk-through observations of the workplace.

    A more formal approach would be to use a standardized checklist to evaluate job tasks against risk factors.

    There are many different types of risk factors for injuries to the muscle and skeleton, some of which are not entirely work-related.

    Risk factors for work-related musculoskeletal disorders are cumulative and can include off-work activities as well. Physical limitations, previous injuries, or existing health problems can contribute to increased risk.

    It is often difficult to determine the impact that work activities versus non-work activities (sport or medical conditions such as rheumatoid arthritis, diabetes, and thyroid conditions) have on the disorder.

    For example, in the general population, non-work causes of lower back pain are probably more common than workplace causes.

    When jobs have risk factors in combinations and high levels, the risk of developing a musculoskeletal disorder will increase. The level of risk also depends on the intensity, frequency, and duration of exposure. Examples of risk factors include repetitive, forceful, or prolonged exertion and pushing, pulling, or carrying heavy objects.

    Risk factors (Actions)

    ·        Repetitive, forceful, or prolonged exertion

    ·        Frequent or heavy lifting

    ·        Pushing, pulling, or carrying of heavy objects

    ·        Prolonged awkward postures

    ·        Work in the cold

    ·        Insufficient pauses and rest breaks for recovery

    Risk factors (Conditions)

    ·        Contact stresses

    ·        Machine-paced work

    ·        Stress

    ·        Unfamiliar or unaccustomed work

    ·        Vibration

     

    Gathering data is a vital step toward the identification of a problem. Checklists can be used to provide the initial identification of a job or task which may put a worker at risk for developing an injury to the muscles or skeleton.

    It is important to understand that the checklist findings must be viewed as a whole to determine if the individual problems suggest the same underlying root cause.

    Control Methods

    Many employers provide engineering controls, such as lift-assist equipment, that go unused or under-used as the employees hurry to complete their tasks.

    Engineering controls reduce or eliminate the condition by modifying or redesigning workstations, environmental conditions, tools and equipment, processes, or materials.

    For instance, a situation was reviewed in the electrical industry, where tasks included hammering, crimping, wrapping, winding, soldering, painting, and various electric motor assemble operations.

    Problem: risk factor involved in these types of tasks included repetitive and forceful exertions, awkward postures, and contact stress. Workers were found to suffer from upper limb and neck illnesses and injuries.

    Solutions: included raised standing surfaces, a modified mallet handle, and low force clamps. Job rotation, training programs, and early reporting were also needed.

    Workstation should be adjustable to fit your body. Furniture and equipment should be positioned to prevent excessive twisting, reaching, and leaning.

    Eyes: Computer monitors should be placed so that the top of the screen is just below eye level.

    Arms and back: Chair should have adjustable armrests to take the load off your neck and shoulders. Chair should have back rests that fit your back.

    Knees and feet: Chair should ne adjustable to allow your knees to be bent at a right angle. Chair should be adjustable to allow your feet to rest flat on the floor. Footrest may be used.

    When your finger are on the keyboard, your wrist should be straight in a neutral position with the upper arm vertical and the forearm at a 90 degree angle to the upper arm.

    Your shoulders should be relaxed and your elbows close to your sides. Reclining and reaching should also be avoided.

    When using the mouse, you should be able to maintain the correct arm and wrist position. The mouse should be at the same levels as the keyboard and the same distance from your body as the keyboard.

    Administrative controls are changes in the workplace that adjust work practices, procedures, and management policies.

    Specific examples include rest breaks, alternative tasks, slower work pace, redesign of work methods, and employee rotation.

    Consider his example of an office work setting. Management reviewed an office environment that involved primarily data entry and tasks involving video display units.

    Problems: risk factors identified from these tasks included repetitive exertions, awkward postures, glare, and poor illumination. Personnel experienced problems with upper limbs, neck, back, and eyestrain.

    Solutions: included reduction glare and improving workstation design. A vision test program and a rest break schedule where also suggested.

    You would use personal protective equipment (PPE), such as gloves, to reduce vibration and prevent injury.

    Always use engineering control s first if possible, followed by administrative controls. Use PPE only as a last resort.

    Studies show that wearing a back belt does not reduce injury rates or the number of lost work days. However, wearing a back belt and having training on lifting techniques may reduce lost work days for people who have had lower back pain in the past.

    Because musculoskeletal disorders involving the back are among the most costly occupational injuries, it is important to review back safety and some basic techniques for prevention of back injuries.

    These techniques include good posture, proper lifting, and the practice of basic exercises, such as stretching.

    To evaluate your posture, stand with your back against a doorframe and slip your hand between the doorframe and the small of your back. Your hand should slide in easily and slightly touch your back and the doorframe.

    When possible, plan jobs to avoid unnecessary lifting. Improper lifting, especially when combined with twisting, is the most common way to injure your back.

    Correct posture: Place feet firmly apart with one foot forward for stability. Bend at the knees (not at the waist) and keep your back as close to vertical as possible.

    Incorrect posture: two of the most common mistake made when lifting are bending at the waist instead of the knees and holding the load too far out in front of you.

    When lifting, tighten your stomach muscle as soon as you lift to support your spine, breathing out as you lift. Do not hold your breath.

    Remember t use your leg muscles instead of your back muscle to lift the load. Do not twist your body while lifting and keep the load close to your body as you lift.

    The best path to a healthy back is to control your weight, exercise, and reduce back stress caused by lifting or poor posture.

    Excessive upper body weight such as potbelly contributes to poor back posture and back pain because of the added stress placed on the components of the back.

    A regular exercise program that includes flexibility and strengthening exercises can help prevent injury or re-injury to your back. Consult your healthcare provider before beginning an exercise program.

    Remember to report signs, symptoms, and hazards of MSDs and make recommendations on appropriate ways to control them. Ways to make these recommendations include e-mail, letters, and notes to your supervisor.

    Recommendations can also be made verbally through an employee representative or by serving on health and safety committees. Always follow applicable workplace procedures and safety and health rule.

     

    Summary:

    Employers are not the only ones with specific responsibilities. You, as an employee, have an important role also.

    Your responsibilities include:

    v Recognizing the signs and symptoms of MSDs and the value of reporting them early

    v Identifying MSD hazards in your job

    v Knowing how to use and evaluate the control measures your employers implements, and

    v Working in ways that will reduce the risks in your job

     
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